Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes

Authors: Alcantara LC, de Oliveira T, Gordon M, Pybus O, Mascarenhas RE, Seixas MO, Goncalves M, Hlela C, Cassol S, Galvao-Castro B.
Title: Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes
Journal: AIDS,20(5):780-2 (2006)

Reference: Alcantara LC, de Oliveira T, Gordon M, Pybus O, Mascarenhas RE, Seixas MO, Goncalves M, Hlela C, Cassol S, Galvao-Castro B. Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes AIDS,20(5):780-2 (2006).

Citation details*

Journal Impact Factor (I.F.): 5.46
Number of citations: 18

*Sources: Thompson I.F. & Google Scholar (Jan 2012)

Abstract

We compared the genetic diversity of the Brazilian human T-cell lymphotropic virus type 1 isolates with those found in KwaZulu-Natal (KZN), South Africa, and with the genetic background of the hosts. The seroprevalence rate in KZN was 1.7%. All sequences belonged to the A subgroup.

The presence of South African sequences in two different clusters from Brazil, and the finding of the beta-globin haplotype in infected hosts are consistent with the transmission of this virus from southern Africa to Brazil

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