Molecular epidemiology: HIV-1 and HCV sequences from Libyan outbreak

Authors: de Oliveira T, Pybus OG, Rambaut A, Salemi M, Cassol S, Ciccozzi M, Rezza G, Gattinara GC, D'Arrigo R, Amicosante M, Perrin L, Colizzi V, Perno CF; Benghazi Study Group.
Title: Molecular epidemiology: HIV-1 and HCV sequences from Libyan outbreak
Journal: Nature,444(7121):836-7 (2006)

Reference: de Oliveira T, Pybus OG, Rambaut A, Salemi M, Cassol S, Ciccozzi M, Rezza G, Gattinara GC, D'Arrigo R, Amicosante M, Perrin L, Colizzi V, Perno CF; Benghazi Study Group. Molecular epidemiology: HIV-1 and HCV sequences from Libyan outbreak Nature,444(7121):836-7 (2006).

Citation details*

Journal Impact Factor (I.F.): 34.48
Number of citations: 52

*Sources: Thompson I.F. & Google Scholar (Jan 2012)

Abstract

In 1998, outbreaks of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) infection were reported in children attending Al-Fateh Hospital in Benghazi, Libya. Here we use molecular phylogenetic techniques to analyse new virus sequences from these outbreaks.

We find that the HIV-1 and HCV strains were already circulating and prevalent in this hospital and its environs before the arrival in March 1998 of the foreign medical staff (five Bulgarian nurses and a Palestinian doctor) who stand accused of transmitting the HIV strain to the children

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