P2 GAG protein

HIV p2 has no known function.




STRUCTURE NOT AVAILABLE
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ViralZone:HIV-1
PDB: not available
SwissProt: P04591 (HIV-1 HXB2 GAG)
Chime Tutorial:  not available
Los Alamos HIV structure DB: not available
EMBL: K03455 [EMBL/GenBank/DDBJ]
BioAfrica: Gag Protein Data Mining Tool


Isoforms:

  • p2 (14 amino acids)

Cleavage site:

Localization:

  • Virion
  • Cell cytoplasm

Function:

  • Spacer peptide
  • No known function

Additional Information:

  • No known functions


Genomic Location: [TOP]

Reference Sequences:

HIV-1 (HXB2):

          10   
|
AEAMSQVTNS ATIM
[download in fasta format]

Length: 14 amino acids
Molecular Weight: 1454 Da
Theoretical pI: 4.00


Protein Domains/Folds/Motifs: [TOP]




Secondary Structure prediction:

SS Prediction - PSIpred

                    10
|
AEAMSQVTNS ATIM
Sec Struct: CCHHHHHHCC CCCC
Confidence: 9135542023 4349

Antigenic Sites - EMBOSS:


Predicted Motifs: Printer-friendly version

N-glycosylation:
N-myristoylation:
Amidation:
Protein kinase C:
Casein kinase II:
Tyrosine kinase:
cAMP / cGMP kinase:
Cell attachment motif:
Asp Protease motif:
Asp Prot Retro motif:
Cysteine-rich Region:
Tryptophan-rich Region:
Zinc-finger CCHC motif:
Leucine Zipper motif:

Protein-Protein Interactions: [TOP]

  • no known interactions


Primary and Secondary Database Entries: [TOP]

Identifiers:

ViralZone: HIV-1
PDB/MMDB: Search for HIV & p2

SwissProt: P04591 (HIV-1 HXB2 GAG)
EMBL: K03455; AAB50258.1 [EMBL/GenBank/DDBJ]

PIR: UNKNOWN
HIV: K03455; UNKNOWN$HXB2
InterPro: none
Pfam: PF00558;UNKNOWN
Prints: unknown
ProDom: PD000472
SCOP: none
BLOCKS: P04591
Prosite: none
ProtoNet: P04591
ProtoMap: P04591
PRESAGE: P04591
Database of Interacting Proteins: P04591
ModBase: P04591
Swiss-2DPAGE: 2D gel

BioAfrica Tools:
- Gag Protein Data Mining Tool provides real-time analysis of HIV-1 Gag isolates
- HIV Structure BLAST searches for similar HIV sequences that have known structures
- HIV Proteomics Resource contains protein sequence and structure analysis tools

Reviews and References: [TOP]

Cite the resource by citing the following paper:
Doherty R et al. BioAfrica's HIV-1 Proteomics Resource: Combining protein data with bioinformatics tools. Retrovirology (2005), 9;2(1):18.

1 - HIV Sequence Compendium 2000
Kuiken CL, Foley B, Hahn B, Korber B, Marx PA, McCutchan F, Mellors JW, Mullins JI, Sodroski J, Wolinksy S.
Theoretical Biol. & Biophys. Group, Los Alamos Nat Lab, LA-UR 01-3860 [Read it online: Compendium]
2 - Retroviruses
Coffin JM, Hughes SH, Varmus HE.
CD-ROM ed. (2002) Cold Spring Harbor Laboratory Press [Read it online: NCBI Bookshelf]
3 - Molecular Characteristics of HIV-1 Subtype C Viruses from KwaZulu-Natal, South Africa:
Implications for Vaccine and Antiretroviral Control Strategies.
Gordon M, De Oliveira T, Bishop K, Coovadia HM, Madurai L, Engelbrecht S, Janse van Rensburg E, Mosam A, Smith A, Cassol S.
Journal of Virology 77(4): 2587-2599 (2003) [pubmed: 12551997]



Page last updated by Tulio de Oliveira.