SATuRN output: reports, clinical cases & publications

Here we provide you with HIV & TB drug resistance information in the form of reports, clinical cases, tweets and publications.

In this new section of the bioafrica.net website, physicians, researchers and public health officials can learn about our drug resistance work and its application to the management of patients failing ARVs and anti-TB therapies.


Reports Clinical Cases

A survey of 10 years of primary drug resistance in South Africa

SATuRN 2011 report, date: 2011

Manasa J, Cassol S, Seebregts C, Newell M-L, de Oliveira T

Surveillance of Transmitted HIV-1 Drug Resistance in South African Provinces from 2005-2009

SATuRN 2011 report, date: 2011

Hunt GM, Ledwaba J, Basson AE, Moyes J, Cohen C, Singh B, Bertagnolio S, Jordan MR, Puren A and Morris L

HIV-1 drug resistance at antiretroviral treatment initiation in children previously exposed to single-dose nevirapine

SATuRN 2011 report, date: 2011

Hunt GM, Coovadia A, Abrams EJ, Sherman G, Meyers T, Morris L and Kuhn L.

Phenotypic Resistance to Etravirine in an HIV-1 Subtype-C Background

SATuRN 2011 report, date: 2011

AE Basson, S-Y Rhee, CM Parry, T de Oliveira, D Pillay, R Shafer and L Morris

In adult patients failing a second-line protease inhibitor regimen lopinavir concentration measurement in plasma or hair are helpful to exclude patients with poor adherence from unnecessary resistance testing

SATuRN 2011 report, date: 2011

van Zyl GU, van Mens TE, McIlleron H, Zeier M, Nachega JB, Decloedt E, Malavazzi C, Smith P, Huang Y, van der Merwe L, Gandhi M, Maartens G.

HIV clinical management: Integrating virtually failure clinics in southern Africa

SATuRN 2011 report, date: 2011

de Oliveira T, Rossouw T, Van Vuuren C, Naidu K, Ndwandwe L, Seebregts C

Southern African HIV Drug Resistance and Clinical Management Workshop

SATuRN 2011 report, date: 2011

de Oliveira T, Seebregts C on behalf of SATuRN

SATuRN output, 15 minutes, All reports...
HIV Case 1 - Adult female with virological failure on first line d4T/3TC/EFV
HIV Case 2 - Adult female patient with virological failure on first line therapy after substitution of EFV to NVP
HIV Case 3 - Adult female patient on treatment for epilepsy with virological failure on TDF/3TC/EFV; previous single dose NVP for PMTCT
HIV Case 4 - Adult female patient with virological and immunological failure after treatment interruption for symptomatic hyperlactataemia
HIV Case 5 - Adolescent initiated on first line therapy of d4T/3TC/EFV with virological and immunological failure
TB Case 1 - HIV-infected TB suspect with previous history of TB treatment: Xpert MTB/RIF test
TB Case 2 - HIV-infected TB suspect with household MDR-TB contact: Xpert MTB/RIF test
TB Case 3 - HIV-infected adult male with a laboratory report showing extensively drug-resistant TB (XDR-TB)
TB Case 4 - HIV-infected TB case with treatment failure on regimen 1 and previous unrecognised isoniazid mono-resistance
TB Case 5 - HIV-infected TB case with smear non-conversion on regimen 1 despite good adherence

SATuRN output, 15 minutes, All cases...

Publications Twitter

Primary drug resistance in South Africa - data from 10 years of surveys.

Manasa J, Katzenstein D, Cassol S, Newell ML, de Oliveira T, AIDS Res Hum Retroviruses (2012), Epub ahead of print:

Genetic Characteristics, Coreceptor Usage Potential and Evolution of Nigerian HIV-1 Subtype G and CRF02_AG Isolate.

Ajoge HO, Gordon ML, de Oliveira T, Green TN, Ibrahim S, Shittu OS, Olonitola SO, Ahmad AA, Ndung'u T, PLoS One (2011), 6(3):e17865

Evaluation of tuberculosis diagnostics: establishing an evidence base around the public health impact.

Lessells RJ, Cooke GS, Newell ML, Godfrey-Faussett P, J Infect Dis (2011), 204:S1187-95

International spread of multidrug-resistant tuberculosis from Tugela Ferry, South Africa.

Cooke GS, Beaton RK, Lessells RJ, John L, Ashworth S, Kon OM, Williams OM, Supply P, Moodley P, Pym AS, Emerg Infect Dis (2011), 17:2035-2037

Poor long-term outcomes for cryptococcal meningitis in rural South Africa.

Lessells RJ, Mutevedzi PC, Heller T, Newell ML, S Afr Med (2011), 101:251-2

Association of age with mortality and virological and immunological response to antiretroviral therapy in rural South African adults.

Mutevedzi PC, Lessells RJ, Rodger AJ, Newell ML, PLoS ONE (2011), 6(7):e21795

Retention in HIV care for individuals not yet eligible for antiretroviral therapy: rural KwaZulu-Natal, South Africa.

Lessells RJ, Mutevedzi PC, Cooke GS, Newell ML., J Acquir Immune Defic Syndr (2011), 56(3):e79-86

Cohort profile: Hlabisa HIV Treatment and Care Programme.

Houlihan C, Bland R, Mutevedzi P, Lessells R, Ndirangu J, Thulare H, Newell ML, Int J Epidemiol (2011), 40:318-26

Surveillance of transmitted antiretroviral drug resistance among HIV-1 infected women attending antenatal clinics in Chitungwiza, Zimbabwe..

Tshabalala M, Manasa J, Zijenah LS, Rusakaniko S, Kadzirange G, Mucheche M, Kassaye S, Johnston E, Katzenstein D, PLoS ONE (2011), 6(6):e21241

Public Database for HIV Drug Resistance in southern Africa.

de Oliveira T, Shafer WR, Seebregts C, for SATuRN, Nature (2010), 464(7289):673

SATuRN output,15 minutes, All publications...




Page design updated by Tulio de Oliveira, 2011