1039 References 68545 Individuals 76278 Time points
140528 Isolates
- 139368 Clinical Isolates, 1160 Lab Isolates
- 140019 HIV-1 Isolates, 281 HIV-2/SIVsm,maq Isolates, 228 NHPL (Non-Human Primate Lentivirus)
150759 Sequences
- 72378 RT Sequences, 71472 Protease Sequences, 6909 Integrase Sequences
- 127859 Sequences from GenBank, 22900 Sequences not in GenBank
2160402 Mutations
- 1342076 RT Mutations, 708707 Protease Mutations, 109619 Integrase Mutations
45808 Phenotype results
- 14193 NRTI, 7867 NNRTI,22863 PI, 885 INI Phenotype results
| Continent | Regions |
|---|
Africa (n = 25528) | South Africa (6378), Cameroon (3230), Uganda (3121), Zambia (1335), Nigeria (1102), Cote d'Ivoire (873), Tanzania (869), Mali (685), Ghana (568), Zimbabwe (527), Botswana (509), Malawi (497), Burkina Faso (490), Kenya (490), Senegal (478), DRC (468), Mozambique (359), Angola (352), Ethiopia (278), Gabon (263), Benin (257), Algeria (253), Burundi (246), CAR (185), Equatorial Guinea (165), Morocco (165), Togo (162), Rwanda (160), Chad (154), Niger (105), Africa (102), Central African Republic (96), Swaziland (94), Guinea (91), Seychelles (84), Libya (68), Sudan (60), Madagascar (60), Zaire (31), Primate Center (31), Guinea-Bissau (19), Liberia (19), Gambia (18), Congo-Brazzaville (12), Dijibouti (7), Somalia (6), Sierra Leone (3), West Africa (3) | Asia (n = 16750) | Taiwan (2616), China (2272), India (2217), Thailand (2060), Vietnam (1983), Japan (1621), Cambodia (823), Israel (617), Korea (589), Singapore (536), Malaysia (459), Uzbekistan (295), Kazakhstan (201), Iran (104), Republic Of Georgia (91), Saudi Arabia (72), Afghanistan (45), Yemen (44), Myanmar (27), Lebanon (26), Indonesia (26), Turkey (14), Nepal (12) | Europe (n = 27566) | Spain (4356), Italy (3648), France (3363), Germany (2549), Portugal (2237), U.K. (1435), Sweden (1161), Denmark (1115), Russia (1040), Belgium (937), Greece (613), Estonia (556), Switzerland (537), Romania (396), Luxembourg (391), Ukraine (364), Cyprus (311), Netherlands (306), Slovenia (252), Poland (242), Republic of Latvia (234), Austria (201), Norway (194), Bulgaria (160), Greenland (150), Serbia (136), Albania (132), Finland (122), Europe (116), Ireland (88), Azerbaijan (82), Hungary (59), Yugoslavia (33), Slovakia (20), Belarus (18), Moldova (12) | North America (n = 57620) | U.S. (50933), Canada (4445), Cuba (1123), Honduras (672), Mexico (265), Trinidad (66), Puerto Rico (31), Barbados (27), Antigua (16), Saint Vincent (12), Saint Lucia (10), Grenada (8), Dominica (6), North America (3), Montserrat (2), Panama (1) | Oceania (n = 826) | Australia (826) | South America (n = 11576) | Brazil (7309), Argentina (2510), Peru (749), Venezuela (521), Chile (327), Colombia (82), Uruguay (38), Ecuador (12), Guyana (12), Suriname (10), Bolivia (6) |
| NRTI component | NNRTI component | PI component | NRTI + PI or NNRTI regimen |
|---|
AZT (2068) DDI (770) D4T (742) 3TC (266) ABC (223) DDC (219) TDF (32)
AZT/3TC (4229) D4T/3TC (3791) DDI/D4T (1663) AZT/DDI (1559) AZT/DDC (806) DDI/3TC (233) 3TC/TDF (191) D4T/ABC (178) 3TC/ABC (161) DDI/ABC (125) AZT/D4T (86) DDC/D4T (75) DDI/TDF (70) AZT/ABC (60) DDC/3TC (60) FTC/TDF (58) D4T/TDF (30)
AZT/3TC/ABC (537) AZT/DDI/3TC (225) D4T/3TC/ABC (125) DDI/D4T/3TC (102) DDI/D4T/ABC (89) 3TC/ABC/TDF (87) AZT/DDC/3TC (72) AZT/D4T/3TC (57) DDI/3TC/TDF (45) AZT/3TC/TDF (38) D4T/3TC/TDF (31) AZT/DDI/DDC (29) DDI/3TC/ABC (24)
AZT/DDI/D4T/3TC (31) AZT/3TC/ABC/TDF (31)
| NVP (3949) EFV (2793) DLV (198) ETR (10) | NFV (2325) IDV (2212) SQV (940) SQVr (746) LPVr (637) RTV (573) IDVr (369) APV (213) APVr (121) ATV (66) ATVr (54) DRVr (43)
NFV/SQV (212) APV/LPVr (54) IDV/SQV (51) NFV/IDV (45) NFV/RTV (27)
| D4T/3TC/NVP (1244) AZT/3TC/IDV (949) AZT/3TC/EFV (774) D4T/3TC/IDV (694) D4T/3TC/EFV (641) AZT/3TC/NVP (626) D4T/3TC/NFV (618) AZT/3TC/NFV (611) AZT/3TC/SQV (348) DDI/D4T/NFV (341) DDI/D4T/EFV (288) DDI/D4T/NVP (219) D4T/3TC/SQV (199) AZT/3TC/RTV (190) D4T/3TC/SQVr (169) D4T/3TC/RTV (149) DDI/D4T/IDV (140) AZT/3TC/SQVr (123) DDI/D4T/SQVr (120) AZT/DDC/SQV (114) D4T/NFV/NVP (104) AZT/3TC/ABC/EFV (101) AZT/3TC/LPVr (98) AZT/3TC/IDVr (95) D4T/3TC/IDVr (72) D4T/3TC/LPVr (69) DDI/D4T/NFV/EFV (69) D4T/3TC/NFV/NVP (68) AZT/DDI/NVP (68) 3TC/TDF/EFV (59) AZT/DDI/NFV (58) AZT/DDI/IDV (56) AZT/DDI/SQV (53) DDI/D4T/SQV (52) |
| Subtype | protease | RT | integrase |
|---|
| PI-naive | PI-treated | RTI-naive | RTI-treated | INI-naive | INI-treated |
|---|
| B | 15474 | 7654 | 12664 | 18662 | 2223 | 106 | | A | 2643 | 180 | 2051 | 702 | 189 | 1 | | C | 5263 | 421 | 4760 | 2857 | 555 | 1 | | D | 982 | 116 | 688 | 442 | 132 | | | F | 814 | 616 | 429 | 481 | 182 | | | G | 1051 | 249 | 848 | 1059 | 104 | | | CRF01_AE | 2382 | 105 | 2053 | 1519 | 363 | | | CRF02_AG | 3090 | 139 | 2222 | 786 | 471 | 2 | | Other | 665 | 104 | 1117 | 532 | 81 | |
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