Open Access HIV & TB drug resistance clinical cases:

Here we provide you with cases published in the HIV/TB Drug Resistance & Clinical Management Case Book. These cases have been presented to over 1000 medical doctors in southern Africa at the annual SATuRN Drug Resistance Workshops.

The objective is to capacitate doctors, nurses and allied medical staff at all levels of the health system to prevent and manage HIV and TB drug resistance.


Report Clinical cases

HIV Case 1 - Adult female with virological failure on first line d4T/3TC/EFV

Authors: Theresa Rossouw, Richard Lessells & Tulio de Oliveira

HIV Case 2 - Adult female patient with virological failure on first line therapy after substitution of EFV to NVP

Authors: Theresa Rossouw, Richard Lessells & Tulio de Oliveira

HIV Case 3 - Adult female patient on treatment for epilepsy with virological failure on TDF/3TC/EFV; previous single dose NVP for PMTCT

Authors: Richard Lessells, Theresa Rossouw & Tulio de Oliveira

HIV Case 4 - Adult female patient with virological and immunological failure after treatment interruption for symptomatic hyperlactataemia

Authors: Theresa Rossouw, Richard Lessells & Tulio de Oliveira

HIV Case 5 - Adolescent initiated on first line therapy of d4T/3TC/EFV with virological and immunological failure

Authors: Theresa Rossouw, Richard Lessells & Tulio de Oliveira

HIV Case 6 - Adult male patient with adverse effects and multiple ARV treatment switches. No virological response to LPV/r based second line therapy

Authors: Theresa Rossouw, Richard Lessells & Tulio de Oliveira

HIV Case 7 - Adolescent case with adherence and toxicity problems

Authors: Theresa Rossouw, Richard Lessells & Tulio de Oliveira

HIV Case 8 - Adult patient initiated on first line d4T/3TC/EFV with low CD4+ cell count (34 cells/ul) and concurrent TB treatment

Authors: Richard Lessells, Theresa Rossouw & Tulio de Oliveira

HIV Case 9 - Adult patient initiated on TDF/3TC/NVP with a low baseline CD4+ cell count, patient transferred from another programme in South Africa

Authors: Richard Lessells, Theresa Rossouw & Tulio de Oliveira

TB Case 1 - HIV-infected TB suspect with previous history of TB treatment: Xpert MTB/RIF test

Authors: Richard Lessells

TB Case 2 - HIV-infected TB suspect with household MDR-TB contact: Xpert MTB/RIF test

Authors: Richard Lessells

TB Case 3 - HIV-infected adult male with a laboratory report showing extensively drug-resistant TB (XDR-TB)

Authors: Richard Lessells

TB Case 4 - HIV-infected TB case with treatment failure on regimen 1 and previous unrecognised isoniazid mono-resistance

Authors: Richard Lessells

TB Case 5 - HIV-infected TB case with smear non-conversion on regimen 1 despite good adherence

Authors: Richard Lessells

SATuRN output, All reports...
SATuRN 2012 report - 2nd Nurses and Health Care Workers Drug Resistance Training for the scale-up of resistance testing in the Free State Province, South Africa
SATuRN 2012 report - SATuRN's Featured Partner: New TB centre at the London School of Hygiene and Tropical Medicine
SATuRN 2012 report - SATuRN's Featured Partner: Division of Medical Virology, Stellenbosh University
SATuRN output, All reports...


Page design updated by Tulio de Oliveira, 2011